Bowen's disease
Overview
Bowen's disease is a very early form of skin cancer that's easily treatable. The main sign is a red, scaly patch on the skin.
Symptoms
Bowen's disease usually appears as a patch on the skin that has clear edges and does not heal. Some people have more than 1 patch. The patch may be: scaly or crustyflat or raisedup to a few centimetres acrossitchy (but not all the time)red or pink on white skin, but this may be harder to see on brown and black skin The patch can appear anywhere on the skin, but is especially common on exposed areas like the lower legs, neck and head. Sometimes they can affect the groin area and, in men, the penis. If the patch bleeds, starts to turn into an open sore (ulcer) or develops a lump, it could be a sign it's turned into squamous cell skin cancer.
Causes
Bowen's disease usually affects people in their 60s and 70s. The exact cause is unclear, but it's been closely linked with: long-term exposure to the sun or use of sunbeds – especially in people with fair skinhaving a weak immune system – for example, it's more common in people taking medicine to suppress their immune system after an organ transplant, or those withAIDSpreviously havingradiotherapytreatmentthehuman papillomavirus (HPV)– a common virus that often affects the genital area and can causegenital warts Bowen's disease does not run in families and it's not infectious.
Treatment
There are a number of treatment options for Bowen's disease. Talk to your dermatologist about which treatment is most suitable for you. The main treatments are: cryotherapy – liquid nitrogen is sprayed on to the affected skin to freeze it. The procedure may be painful and the skin may remain a bit uncomfortable for a few days. The affected skin will scab over and fall off within a few weeks.imiquimod cream or chemotherapy cream (such as 5-fluorouracil) – this is applied to the affected skin regularly for a few weeks. It may cause your skin to become red and inflamed before it gets better.curettage and cautery – the affected area of skin is scraped away underlocal anaesthetic, where the skin is numbed, and heat or electricity is used to stop any bleeding, leaving the area to scab over and heal after a few weeks.photodynamic therapy (PDT)– a light-sensitive cream is applied to the affected skin and a laser is directed on to the skin a few hours later to destroy the abnormal cells. The treatment session usually lasts between 8 to 45 minutes. You may need more than 1 session.surgery – the abnormal skin is cut out under local anaesthetic and stitches may be needed afterwards. In some cases, your dermatologist may just advise monitoring your skin closely – for example, if it's very slow growing and they feel the side effects of treatment will outweigh the benefits. After having treatment for Bowen's disease, you may need follow-up appointments with your dermatologist or GP to see if you need any further treatment. If you had surgery, you may need to have any stitches removed at your GP surgery 5 to 14 days later or once your wound has healed. Sometimes dissolvable stitches are used that do not need to be removed. If you had a dressing on your wound, you may need to go to your GP or the hospital to have it changed. After treatment: see a GP if an existing patch starts to bleed, change in appearance or develops a lump – do not wait for your follow-up appointmentsee a GP if you notice any new patches on your skinmake sure you protect your skin from the sun – wear protective clothing and use a sunscreen with a high sun protection factor (SPF) of at least 30 Get more advice on sunscreen and sun safety