Charcot-Marie-Tooth disease

Overview

Charcot-Marie-Tooth disease (CMT) is a group of inherited conditions that damage the peripheral nerves.

Causes

CMT is caused by an inherited fault in one of the many genes responsible for the development of the peripheral nerves. This fault means the nerves become damaged over time. A child with CMT may have inherited the genetic fault responsible for the condition from 1 or both of their parents. There's no single faulty gene that causes CMT. There are many types of CMT that are caused by different genetic faults and these can be inherited in several different ways. The chances of passing CMT to your child depend on the specific genetic faults you and your partner carry. Find out more about the causes of CMT